opioid-related disorders

Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html

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Study Counts

Type	Study_count
Total_Studies	465
interventional	390
Observational	70
Registry	5

Studies over Time by Start Date

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Interventional Trials

Intervention Type

intervention_type	Study_Count
Drug	188
Behavioral	69
Drug|placebo	62
Other	17
Behavioral|Drug	14
Device	11
Drug|Other	10
Behavioral|Other	5
Procedure	4
Behavioral|Drug|Other	2
Combination Product	2
Other|Procedure	2
Behavioral|Dietary Supplement|Procedure	1
Device|Drug	1
Diagnostic Test	1
Drug|Procedure	1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country	Study_Count
United States	333
NA	13
Norway	7
Canada	6
Russian Federation	3
Taiwan	3
China	2
Finland	2
Lithuania	2
Malaysia	2
Sweden	2
Australia	1
Chile	1
France	1
Germany	1
Germany|Sweden|Austria|Czech Republic	1
Iran, Islamic Republic of	1
Netherlands	1
Switzerland	1
Ukraine	1
United Kingdom	1
United States|Austria|Canada	1
United States|Canada	1
United States|China	1
United States|Malaysia	1
United States|Russian Federation	1

Sites per Study

Site_count	Study_Count
1	320
2	36
3	5
4	3
5	2
6	2
7	1
8	2
10	1
11	2
12	3
14	1
15	2
16	1
18	3
20	1
28	1
29	1
36	1
38	1
42	1

Phase

Phase	Study_Count
Phase 2	110
N/A	107
Phase 3	50
Phase 1	46
Phase 4	40
Phase 1/Phase 2	16
Phase 2/Phase 3	14
Early Phase 1	7

Number of Arms

Number_of_Arms	Count_of_Studies
1	46
2	182
3	42
4	24
5	10
6	2
7	3
8	2
12	1
15	1
NA	77

Enrollment Metrics by Phase

Measure	Early.Phase.1	N.A	Phase.1	Phase.1.Phase.2	Phase.2	Phase.2.Phase.3	Phase.3	Phase.4
Min.	25.0000	4.0000	0.00000	6.00	0.00000	6.0000	0.00	0.000
1st Qu.	54.0000	37.0000	6.50000	11.75	0.00000	36.5000	52.25	36.250
Median	64.0000	67.0000	28.50000	20.00	17.50000	84.5000	167.00	60.000
Mean	123.8571	155.9813	40.04348	46.25	49.12037	111.5714	232.90	168.075
3rd Qu.	185.0000	180.0000	50.00000	79.00	58.25000	142.0000	296.75	208.750
Max.	300.0000	3144.0000	208.00000	151.00	382.00000	308.0000	1015.00	900.000

Trial Group Type

group_type	Group_Count
Experimental	356
Active Comparator	236
Placebo Comparator	86
NA	77
No Intervention	38
Other	31
Sham Comparator	11

Intervention Model

intervention_model	Study_Count
Parallel Assignment	209
Single Group Assignment	62
Crossover Assignment	55
NA	45
Factorial Assignment	16
Sequential Assignment	3

Primary Purpose

primary_purpose	Study_Count
Treatment	310
Prevention	25
Health Services Research	15
Basic Science	14
NA	12
Other	8
Supportive Care	4
Device Feasibility	1
Diagnostic	1

Observational Studies

Studies by Country

Country	Study_Count
United States	46
NA	13
France	4
Australia	1
Austria	1
Denmark	1
Italy	1
Malaysia	1
Norway	1
United Kingdom	1

Sites per Study

Site_count	Study_Count
1	57
2	8
3	1
8	1
24	1
31	1
35	1

Enrollment Metrics

Measure	Observational
Min	6.0
1st Qu	31.0
Median	128.0
Mean	327285.1
3rd Qu	523.0
Max	22375112.0

Observation Model

observational_model	Study_Count
Cohort	36
Other	13
Case-Only	12
NA	5
Ecologic or Community	2
Case-Control	1
Case Control	1

Time Perspective

time_perspective	Study_Count
Prospective	53
Cross-Sectional	9
Retrospective	7
Other	1

Registries

Studies by Country

Country	Study_Count
France	1
Germany	1
Korea, Republic of	1
Sweden	1
United States	1

Sites per Study

Site_count	Study_Count
1	4
18	1

Enrollment Metrics

Measure	Registries
Min	60.0
1st Qu	100.0
Median	258.0
Mean	548.6
3rd Qu	325.0
Max	2000.0

Registry Model

observational_model	Study_Count
Cohort	2
Other	2
Case-Control	1

Time Perspective

time_perspective	Study_Count
Prospective	5

Follow-up

target_duration	Study_Count
12 Months	2
24 Weeks	1
3 Months	1
36 Months	1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id	brief_title	link	overall_status	source	primary_completion_date
NCT04413552	INDV-2000 First in Human	https://ClinicalTrials.gov/show/NCT04413552	Recruiting	Indivior Inc.	2020-12-01
NCT03918850	Medication Treatment for Opioid Use Disorder in Expectant Mothers	https://ClinicalTrials.gov/show/NCT03918850	Recruiting	University of Cincinnati	2023-12-31
NCT03911466	Medication Treatment for Opioid Use Disorder in Expectant Mothers: Conceptual Model Assessments Sub-study	https://ClinicalTrials.gov/show/NCT03911466	Recruiting	University of Cincinnati	2023-12-31
NCT03718065	Impact of Lofexidine on Stress, Craving and Opioid Use	https://ClinicalTrials.gov/show/NCT03718065	Recruiting	Medical University of South Carolina	2024-04-01
NCT03684681	The Navigator Trial	https://ClinicalTrials.gov/show/NCT03684681	Recruiting	Rhode Island Hospital	2020-10-31
NCT03396276	Houston Emergency Opioid Engagement System	https://ClinicalTrials.gov/show/NCT03396276	Recruiting	The University of Texas Health Science Center, Houston	2020-11-01
NCT03377855	Addressing Origins of the Opioid Epidemic by Improving Prescribing for Opioid-Naive Patients	https://ClinicalTrials.gov/show/NCT03377855	Completed	Weill Medical College of Cornell University	2019-12-31
NCT03368794	Naloxone to TReatment Entry in the Emergency Setting	https://ClinicalTrials.gov/show/NCT03368794	Recruiting	Region Skane	2019-07-28
NCT03822962	Pain Management Following Sinus Surgery	https://ClinicalTrials.gov/show/NCT03822962	Recruiting	University of Nebraska	2020-12-31
NCT03363243	Advancing STOP: Self-regulation Therapy for Opioid Addiction and Pain	https://ClinicalTrials.gov/show/NCT03363243	Recruiting	University of Colorado, Denver	2021-03-31
NCT03345173	Facilitating Rapid Naltrexone Initiation	https://ClinicalTrials.gov/show/NCT03345173	Recruiting	New York State Psychiatric Institute	2021-10-31
NCT03334903	Gabapentin Regimens and Their Effects on Opioid Consumption	https://ClinicalTrials.gov/show/NCT03334903	Completed	Brigham and Women’s Hospital	2019-04-24
NCT03320889	Hepatitis C Education for Pregnant Women With Opiate Dependence - Phase 2	https://ClinicalTrials.gov/show/NCT03320889	Completed	TriHealth Inc.	2019-08-26
NCT03306368	Youth Opioid Recovery Support: A Developmentally-specific Intervention for Home Delivery of Extended Release Naltrexone	https://ClinicalTrials.gov/show/NCT03306368	Completed	Potomac Health Foundations	2019-06-01
NCT03305666	Trial of Injected Liposomal Bupivacaine vs Bupivacaine Infusion After Surgical Stabilization of Rib Fractures	https://ClinicalTrials.gov/show/NCT03305666	Recruiting	Denver Health and Hospital Authority	2020-04-30
NCT03287180	Adolescent Community Reinforcement Approach in Combination With Buprenorphine/Naloxone for Severe Opioid Use	https://ClinicalTrials.gov/show/NCT03287180	Recruiting	Emory University	2020-08-30
NCT03278496	Recovery Housing and Drug Abuse Treatment Outcome	https://ClinicalTrials.gov/show/NCT03278496	Completed	Johns Hopkins University	2008-06-30
NCT03235154	A Pilot Study of Treating HCV at a Psychiatrist-staffed Outpatient Addiction Clinic	https://ClinicalTrials.gov/show/NCT03235154	Active, not recruiting	Community Research Initiative of New England	2020-04-30
NCT03190954	Brain Dopaminergic Signaling in Opioid Use Disorders	https://ClinicalTrials.gov/show/NCT03190954	Recruiting	National Institutes of Health Clinical Center (CC)	2024-12-31
NCT03150173	Onsite Buprenorphine Treatment at Syringe Exchange Programs	https://ClinicalTrials.gov/show/NCT03150173	Recruiting	Montefiore Medical Center	2021-06-30
NCT03143855	Drug Interaction and Subjective Effects of Compounds for Opioid Use Disorder	https://ClinicalTrials.gov/show/NCT03143855	Completed	Virginia Commonwealth University	2019-04-05
NCT03134092	The Life STORRIED Study	https://ClinicalTrials.gov/show/NCT03134092	Completed	University of Pennsylvania	2019-08-07
NCT03129347	Pharmacokinetic Evaluation of Nalmefene Administered Intranasally to Healthy Volunteers	https://ClinicalTrials.gov/show/NCT03129347	Completed	National Institute on Drug Abuse (NIDA)	2017-06-09
NCT03089983	Addiction, HIV and Tuberculosis in Malaysian Criminal Justice Settings	https://ClinicalTrials.gov/show/NCT03089983	Recruiting	Yale University	2022-04-30
NCT03048643	Combining Opioid Addiction Treatment Services With CARe for Infectious Endocarditis	https://ClinicalTrials.gov/show/NCT03048643	Completed	University of Kentucky	2018-10-02
NCT03015597	Pilot Study of Contingency Management for Smoking Cessation	https://ClinicalTrials.gov/show/NCT03015597	Completed	King’s College London	2017-09-30
NCT02997644	Impact of Different Educational Approaches on Post-operative Opiate Utilization After Elective Lower Extremity Surgery	https://ClinicalTrials.gov/show/NCT02997644	Completed	Brooke Army Medical Center	2019-04-30
NCT02978417	Feasibility Study of Extended-release Naltrexone (Vivitrol) in Drug Court Settings	https://ClinicalTrials.gov/show/NCT02978417	Completed	Duke University	2019-06-30
NCT02922959	A Tailored, Peer-delivered Intervention to Reduce Recurring Opioid Overdoses	https://ClinicalTrials.gov/show/NCT02922959	Completed	University of Cincinnati	2019-07-25
NCT02896296	Open-Label Treatment Extension Study	https://ClinicalTrials.gov/show/NCT02896296	Completed	Indivior Inc.	2017-08-23
NCT02867124	Long-acting Naltrexone for Pre-release Prisoners	https://ClinicalTrials.gov/show/NCT02867124	Recruiting	Friends Research Institute, Inc.	2020-08-31
NCT02804152	Program for Pain & Prescription Opioid Use in Pregnancy	https://ClinicalTrials.gov/show/NCT02804152	Active, not recruiting	Medical University of South Carolina	2019-01-31
NCT02801357	Study to Evaluate the Exposures of Lofexidine and Its Major Metabolites in Subjects Seeking Buprenorphine Dose Reduction	https://ClinicalTrials.gov/show/NCT02801357	Completed	US WorldMeds LLC	2016-08-31
NCT02774954	Change the Cycle: An RCT to Prevent Injection Initiation	https://ClinicalTrials.gov/show/NCT02774954	Active, not recruiting	University of Southern California	2018-12-31
NCT02750748	Pharmacokinetic Evaluation of Intranasal, Intramuscular, and Oral Naltrexone in Healthy Volunteers	https://ClinicalTrials.gov/show/NCT02750748	Completed	National Institute on Drug Abuse (NIDA)	2016-09-30
NCT02696096	Neuroimaging Predictors of Relapse During Treatment for Opiate Dependence	https://ClinicalTrials.gov/show/NCT02696096	Completed	Butler Hospital	2020-02-29
NCT02674711	Study of Opioid Use After Lumbar and Cervical Spine Surgery	https://ClinicalTrials.gov/show/NCT02674711	Completed	Brooke Army Medical Center	2017-02-28
NCT02616523	Influence of Dexmedetomidine and Lidocaine on Opioid Consumption in Laparoscopic Intestine Resection	https://ClinicalTrials.gov/show/NCT02616523	Completed	University Medical Centre Ljubljana	2015-06-30
NCT02602795	Distress Tolerance and HIV Prevention With XR-NTX Initiation in Opioid Dependence	https://ClinicalTrials.gov/show/NCT02602795	Completed	Rhode Island Hospital	2018-01-31
NCT02593474	Medication-Assisted Treatment for Youth With Substance Use Disorders	https://ClinicalTrials.gov/show/NCT02593474	Completed	New York State Psychiatric Institute	2018-04-30
NCT02586896	Comparing Interventions for Opioid Dependent Patients Presenting in Medical Emergency Departments	https://ClinicalTrials.gov/show/NCT02586896	Completed	NYU Langone Health	2019-04-23
NCT03098407	Opioid Dependence Treatment Therapies in Pregnancy	https://ClinicalTrials.gov/show/NCT03098407	Active, not recruiting	University of Pittsburgh	2019-10-09
NCT02526212	Buprenorphine Group Medical Visits in Primary Care	https://ClinicalTrials.gov/show/NCT02526212	Completed	Montefiore Medical Center	2019-05-31
NCT02572089	Pharmacokinetic Evaluation of Intranasal and Intramuscular Naloxone in Healthy Volunteers	https://ClinicalTrials.gov/show/NCT02572089	Completed	National Institute on Drug Abuse (NIDA)	2015-01-31
NCT00000319	Buprenorphine Maintenance Dose Schedule and Treatment Setting - 2	https://ClinicalTrials.gov/show/NCT00000319	Completed	Yale University	NA
NCT03389750	A Study to Evaluate the Abuse Potential of Oxymorphone Compared to Other Mu Opioid Agonists.	https://ClinicalTrials.gov/show/NCT03389750	Recruiting	New York State Psychiatric Institute	2020-12-31
NCT00023283	Counseling Conditions for Buprenorphine in a Primary Care Clinic - 1	https://ClinicalTrials.gov/show/NCT00023283	Completed	Yale University	2003-12-31
NCT02548728	Oxytocin Treatment of Opioid Dependence	https://ClinicalTrials.gov/show/NCT02548728	Completed	University of North Carolina, Chapel Hill	2016-12-31
NCT00000216	Buprenorphine Maintenance for Cocaine Abusing Opioid Addicts - 1	https://ClinicalTrials.gov/show/NCT00000216	Completed	Yale University	NA
NCT02543944	Improving Treatment Outcomes for Prescription Opioid Dependence	https://ClinicalTrials.gov/show/NCT02543944	Recruiting	University of Arkansas	2020-06-30
NCT02539823	Acute and Short-term Effects of CBD on Cue-induced Craving in Drug-abstinent Heroin-dependent Humans	https://ClinicalTrials.gov/show/NCT02539823	Completed	Hurd,Yasmin, Ph.D.	2017-05-24
NCT02510014	Safety and Tolerability Study of Depot Buprenorphine in Treatment Seeking Subjects With Opioid Use Disorder	https://ClinicalTrials.gov/show/NCT02510014	Completed	Indivior Inc.	2017-01-31
NCT02502175	Comparing Opium Tincture (OT) With Methadone for Medication-assisted Treatment of Opioid Use Disorder	https://ClinicalTrials.gov/show/NCT02502175	Completed	University of British Columbia	2018-03-08
NCT02496403	Buprenorphine and Substance Abuse Services for Prescription Opioid Dependence	https://ClinicalTrials.gov/show/NCT02496403	Completed	Kaiser Permanente	2019-05-31
NCT02477267	Study of Buprenorphine-Naloxone Sublingual Spray and Suboxone® Sublingual Film in Healthy Volunteers	https://ClinicalTrials.gov/show/NCT02477267	Completed	INSYS Therapeutics Inc	2015-07-31
NCT02440152	The Effectiveness of Deep Brain Stimulation for Opioid Relapse Prevention	https://ClinicalTrials.gov/show/NCT02440152	Recruiting	Ruijin Hospital	2019-07-31
NCT02437344	Glutamatergic Modulation to Facilitate Naltrexone Initiation in Opioid Dependence	https://ClinicalTrials.gov/show/NCT02437344	Completed	New York State Psychiatric Institute	2016-12-31
NCT02411357	Improving Effective Contraceptive Use Among Opioid-maintained Women: Stage II	https://ClinicalTrials.gov/show/NCT02411357	Active, not recruiting	University of Vermont	2019-03-06
NCT02396979	Intervention of HIV, Drug Use and the Criminal Justice System in Malaysia	https://ClinicalTrials.gov/show/NCT02396979	Completed	Yale University	2014-12-31
NCT02372591	Study of the Treatment of Experimental Pain in Buprenorphine Maintained Persons With Chronic Musculoskeletal Pain	https://ClinicalTrials.gov/show/NCT02372591	Completed	Johns Hopkins University	2017-06-30
NCT02362256	The Comparison of Stress Response to Rapid Opioid Detoxification Applying Different Methods of Opioid Antagonism	https://ClinicalTrials.gov/show/NCT02362256	Completed	Vilnius University	2014-06-30
NCT02360007	Interim Buprenorphine: Leveraging Medication + Technology to Bridge Delays in Treatment Access	https://ClinicalTrials.gov/show/NCT02360007	Completed	University of Vermont Medical Center	2016-06-30
NCT02359006	The Effects of Minocycline in Opioid-maintained Patients	https://ClinicalTrials.gov/show/NCT02359006	Completed	Yale University	2017-04-19
NCT02357901	Treatment Seeking Participants With Opioid Use Disorders Assessing Tolerability of Depot Injections of Buprenorphine	https://ClinicalTrials.gov/show/NCT02357901	Completed	Indivior Inc.	2016-04-29
NCT02345655	On-site Evaluation of Substances Consumption on Opiate Maintenance	https://ClinicalTrials.gov/show/NCT02345655	Recruiting	University Hospital, Toulouse	2020-04-30
NCT02324725	Biomarkers of Injectable Extended Release Naltrexone Treatment	https://ClinicalTrials.gov/show/NCT02324725	Active, not recruiting	University of Pennsylvania	2021-10-31
NCT02294253	Buprenorphine/Naloxone Stabilization and Induction Onto Injection Naltrexone	https://ClinicalTrials.gov/show/NCT02294253	Completed	New York State Psychiatric Institute	2017-12-31
NCT02282306	Phone Interview to Prevent Recurring Opioid Overdoses	https://ClinicalTrials.gov/show/NCT02282306	Completed	University of Cincinnati	2015-02-28
NCT02252068	Study of Treatment for Opioid Dependence and Anxiety Disorders	https://ClinicalTrials.gov/show/NCT02252068	Completed	Mclean Hospital	2019-10-24
NCT02243670	Using Artificial Intelligence To Monitor Medication Adherence in Opioid Replacement Therapy	https://ClinicalTrials.gov/show/NCT02243670	Completed	AiCure	2017-03-31
NCT02200406	Desvenlafaxine in Opioid-Dependent Patients	https://ClinicalTrials.gov/show/NCT02200406	Completed	Centre hospitalier de l’Université de Montréal (CHUM)	2017-01-31
NCT02187198	Buprenorphine Treatment for Opioid Dependence	https://ClinicalTrials.gov/show/NCT02187198	Active, not recruiting	Yale University	2021-02-01
NCT02180659	A Study of Adult Outpatients With Opioid Dependence Transitioned From a Daily SL Buprenorphine to Probuphine® Subdermal Implants	https://ClinicalTrials.gov/show/NCT02180659	Completed	Titan Pharmaceuticals	2015-05-31
NCT02152397	Safety and Health Intervention Project	https://ClinicalTrials.gov/show/NCT02152397	Completed	University of Michigan	2016-12-31
NCT02093559	Repeated-dose Brief Intervention to Reduce Overdose and Risk Behaviors Among Naloxone Recipients	https://ClinicalTrials.gov/show/NCT02093559	Completed	San Francisco Department of Public Health	2016-12-31
NCT01315184	Study of Computer-Based Treatment for Drug Dependence	https://ClinicalTrials.gov/show/NCT01315184	Completed	Yale University	2011-07-31
NCT01311778	Study to Test the Safety and Efficacy of Cannabidiol as a Treatment Intervention for Opioid Relapse	https://ClinicalTrials.gov/show/NCT01311778	Completed	Hurd,Yasmin, Ph.D.	2011-10-31
NCT01275599	Drug-Drug Interaction Study Between Telaprevir and Buprenorphine	https://ClinicalTrials.gov/show/NCT01275599	Completed	Vertex Pharmaceuticals Incorporated	2011-04-30
NCT02038790	Usability of Zubsolv Sublingual Tablets 5.7/1.4 to Suboxone Sublingual Film 8/2 In Buprenorphine/Naloxone Treated Opioid Dependent Population	https://ClinicalTrials.gov/show/NCT02038790	Completed	Indivior Inc.	2013-11-30
NCT04454645	Intervening With Opioid-Dependent MothersMothers and Infants	https://ClinicalTrials.gov/show/NCT04454645	Recruiting	University of Delaware	2025-03-31
NCT01999946	Extended-Release Naltrexone Opioid Treatment at Jail Re-Entry	https://ClinicalTrials.gov/show/NCT01999946	Active, not recruiting	NYU Langone Health	2019-05-28
NCT01967641	Prescription Opioid Abuse Among Pain Patients: Predictors of Relapse	https://ClinicalTrials.gov/show/NCT01967641	Completed	New York State Psychiatric Institute	2011-06-30
NCT01965704	Can Ondansetron Prevent Neonatal Abstinence Syndrome (NAS) in Babies Born to Narcotic-dependent Women	https://ClinicalTrials.gov/show/NCT01965704	Recruiting	Stanford University	2021-03-30
NCT01913418	Clinical Efficacy and Serum Proteomic Profiling of Suan-Zao-Ren Tang for Sleep Disturbance During Methadone Maintenance	https://ClinicalTrials.gov/show/NCT01913418	Completed	China Medical University, Taiwan	2014-03-31
NCT01909076	Transforming Opioid Prescribing in Primary Care	https://ClinicalTrials.gov/show/NCT01909076	Completed	Boston Medical Center	2016-03-31
NCT01908842	Efficacy of BNX Sublingual Tablets Versus BNX Sublingual Film for Treatment of Opioid-Dependent Adults	https://ClinicalTrials.gov/show/NCT01908842	Completed	Orexo AB	2014-04-30
NCT01903005	Multi-Center, Open-Label, 24-Week Study of OX219 Safety and Efficacy for Maintenance Treatment of Opioid Dependence	https://ClinicalTrials.gov/show/NCT01903005	Completed	Orexo AB	2014-09-30
NCT01895270	Improving Buprenorphine Detoxification Outcomes With Isradipine	https://ClinicalTrials.gov/show/NCT01895270	Completed	University of Arkansas	2016-04-30
NCT01895036	Nalrexone Facilitated Discontinuation of Buprenorphine	https://ClinicalTrials.gov/show/NCT01895036	Completed	New York State Psychiatric Institute	2013-09-30
NCT01894087	Safety & Prevention Outcomes Study	https://ClinicalTrials.gov/show/NCT01894087	Completed	University of Michigan	2015-01-31
NCT01882361	Opioid Relapse & HIV Risk: 48 Versus 24 Weeks of Injectable Extended Release Naltrexone	https://ClinicalTrials.gov/show/NCT01882361	Active, not recruiting	University of Pennsylvania	2020-07-31
NCT01880086	Clomiphene Citrate for the Treatment of Low Testosterone Associated With Chronic Opioid Pain Medication Administration	https://ClinicalTrials.gov/show/NCT01880086	Completed	Weill Medical College of Cornell University	2016-03-31
NCT01873989	Testosterone Replacement for Male Opioid Agonist Maintained Patients	https://ClinicalTrials.gov/show/NCT01873989	Completed	Yale University	2015-01-31
NCT01863251	Atomoxetine for ATS and Opioid Dependence During Buprenorphine Maintenance Treatment in Malaysia	https://ClinicalTrials.gov/show/NCT01863251	Completed	Yale University	2014-08-31
NCT01863186	Efficacy, Safety and Dose-Response Study Followed by Open-Label Study of Lofexidine Treatment of Opioid Withdrawal	https://ClinicalTrials.gov/show/NCT01863186	Completed	US WorldMeds LLC	2014-11-30
NCT01848054	Study to Assess Efficacy and Safety of BNX Sublingual Tablets for the Induction of Treatment of Opioid Dependence	https://ClinicalTrials.gov/show/NCT01848054	Completed	Orexo AB	2014-01-31
NCT01846481	A Randomized, 4-sequence, 2-period, Double-blind, Placebo Controlled Study With a DSM-IV-TR Diagnosis of Cocaine Abuse	https://ClinicalTrials.gov/show/NCT01846481	Completed	Indivior Inc.	2013-06-30
NCT01843751	Dane County Drug Court Study for Addicted Offenders	https://ClinicalTrials.gov/show/NCT01843751	Completed	University of Wisconsin, Madison	2016-02-29
NCT01820442	Pharmacokinetic & Pharmacodynamic Interaction of Lofexidine and Buprenorphine in Buprenorphine Maintained Patients	https://ClinicalTrials.gov/show/NCT01820442	Completed	US WorldMeds LLC	2013-09-30
NCT01779973	Remote Observed Dosing to Increase Suboxone Compliance	https://ClinicalTrials.gov/show/NCT01779973	Completed	University of Pennsylvania	2013-09-30
NCT01761110	Pilot Test of a Community-based Buprenorphine Treatment Intervention	https://ClinicalTrials.gov/show/NCT01761110	Completed	Albert Einstein College of Medicine	2014-02-28
NCT01759446	Abuse Potential of Intranasal VYCAVERT Tablets (Hydrocodone Bitartrate/Acetaminophen) in Recreational Opioid Users	https://ClinicalTrials.gov/show/NCT01759446	Completed	Acura Pharmaceuticals Inc.	2013-04-30
NCT01741350	Testing a Community-Friendly Risk Reduction Intervention for Injection Drug Users	https://ClinicalTrials.gov/show/NCT01741350	Completed	University of Connecticut	2011-05-31
NCT01740414	Effects of Ibudilast on Oxycodone Self-administration in Opioid Abusers	https://ClinicalTrials.gov/show/NCT01740414	Completed	New York State Psychiatric Institute	2015-12-31
NCT01738503	Multiple Dose Pharmacokinetics Depot Buprenorphine in Opioid-Dependent Subjects	https://ClinicalTrials.gov/show/NCT01738503	Completed	Indivior Inc.	2014-05-31
NCT01733693	Neurocognitive Effects of Opiate Agonist Treatment	https://ClinicalTrials.gov/show/NCT01733693	Completed	Albert Einstein College of Medicine	2017-06-30
NCT01728909	Methadone Oxytocin Option	https://ClinicalTrials.gov/show/NCT01728909	Completed	University of California, San Francisco	2014-10-31
NCT01718964	Acute Effects of Cortisol on Heroin Craving in Opioid Dependence (Ghost-Basel)	https://ClinicalTrials.gov/show/NCT01718964	Completed	University of Basel	2013-07-31
NCT01717963	Naltrexone vs Buprenorphine-Naloxone for Opioid Dependence in Norway	https://ClinicalTrials.gov/show/NCT01717963	Completed	University of Oslo	2016-08-31
NCT01690546	Low Dose Naltrexone-buprenorphine Transfer to Vivitrol Injection in Opioid Dependence	https://ClinicalTrials.gov/show/NCT01690546	Completed	Duke University	2015-02-28
NCT01666119	An Open Label Study To Assess The Safety And Tolerability Of BEMA® Buprenorphine NX In Opioid Dependent Subjects	https://ClinicalTrials.gov/show/NCT01666119	Completed	BioDelivery Sciences International	2013-01-31
NCT01650649	Main Study of Lofexidine and Methadone Pharmacodynamic Interaction in Methadone Maintained Patients	https://ClinicalTrials.gov/show/NCT01650649	Completed	US WorldMeds LLC	2012-12-31
NCT01645033	Computer-based Cognitive Behavioral Therapy for Risky Behaviors in Opioid Dependent Patients	https://ClinicalTrials.gov/show/NCT01645033	Completed	Yale University	2013-12-31
NCT01642030	Study of the Treatment of Experimental Pain in Opioid Dependent Persons on Methadone or Buprenorphine Maintenance	https://ClinicalTrials.gov/show/NCT01642030	Completed	Johns Hopkins University	2017-07-31
NCT01605539	Acute and Short-term Effects of Cannabidiol Admin on Cue-induced Craving in Drug-abstinent Heroin Dependent Humans	https://ClinicalTrials.gov/show/NCT01605539	Completed	Hurd,Yasmin, Ph.D.	2013-10-31
NCT01595867	Abuse Potential Assessment of Intranasally Administered EMBEDA Compared To Morphine Sulfate Controlled Release And Placebo	https://ClinicalTrials.gov/show/NCT01595867	Completed	Pfizer	2011-01-31
NCT01590251	Yoga for Pain and Opioid Dependence	https://ClinicalTrials.gov/show/NCT01590251	Completed	Yale University	2014-11-30
NCT01582347	Transfer of Subjects From Subutex/Suboxone to RBP-6300	https://ClinicalTrials.gov/show/NCT01582347	Completed	Indivior Inc.	2012-11-30
NCT01558934	Pilot Study of Lofexidine and Methadone Pharmacodynamic Interaction in Methadone Maintained Patients	https://ClinicalTrials.gov/show/NCT01558934	Completed	US WorldMeds LLC	2012-04-30
NCT01556425	The Separate and Combined Effects of Vivitrol and Opiate Abstinence Reinforcement in the Treatment of Opioid Dependence	https://ClinicalTrials.gov/show/NCT01556425	Completed	Johns Hopkins University	2016-12-12
NCT01556087	Distress Tolerance and Buprenorphine	https://ClinicalTrials.gov/show/NCT01556087	Completed	Butler Hospital	2014-02-28
NCT01530542	A Clinical Study To Characterize The Pharmacokinetics And The Effects Of Food On Oxycodone In Healthy Volunteers	https://ClinicalTrials.gov/show/NCT01530542	Completed	Pfizer	2010-09-30
NCT01527994	Aprepitant Effects in Intravenous Heroin Dependence	https://ClinicalTrials.gov/show/NCT01527994	Completed	New York University	2014-06-30
NCT01512433	The Clinical Efficacy of Acupuncture as an Adjunct to Methadone Treatment Services for Heroin Addicts	https://ClinicalTrials.gov/show/NCT01512433	Completed	China Medical University, Taiwan	2012-03-31
NCT01505101	Mindfulness-Oriented Recovery Enhancement for Chronic Pain Patients Receiving Opioid Therapy	https://ClinicalTrials.gov/show/NCT01505101	Completed	Florida State University	2013-07-31
NCT01471145	Depot Naltrexone Mechanism of Action in Heroin Dependent Patients Using fMRI and SPECT	https://ClinicalTrials.gov/show/NCT01471145	Completed	Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)	2014-10-31
NCT01453374	A Study of VIVITROL in the Prevention of Re-arrest and Re-incarceration	https://ClinicalTrials.gov/show/NCT01453374	Completed	Alkermes, Inc.	2014-05-31
NCT01447212	Study to Assess Longer-term Opioid Medication Effectiveness (SALOME)	https://ClinicalTrials.gov/show/NCT01447212	Completed	University of British Columbia	2014-06-30
NCT01442493	Reengineering Methadone Treatment Study of Patient-centered Methadone Treatment	https://ClinicalTrials.gov/show/NCT01442493	Completed	Friends Research Institute, Inc.	2015-04-30
NCT01425060	Improving Effective Contraceptive Use Among Opioid-maintained Women	https://ClinicalTrials.gov/show/NCT01425060	Completed	University of Vermont	2014-06-30
NCT01416584	A Bridge to Treatment: The Therapeutic Workplace and Methadone Treatment	https://ClinicalTrials.gov/show/NCT01416584	Completed	Johns Hopkins University	2013-10-31
NCT01395784	Effects of Pioglitazone, a PPARgamma Receptor Agonist, on the Abuse Liability of Oxycodone	https://ClinicalTrials.gov/show/NCT01395784	Completed	New York State Psychiatric Institute	2014-01-31
NCT01393392	Developing a Smoking Cessation Intervention for Methadone Maintained Smokers	https://ClinicalTrials.gov/show/NCT01393392	Completed	Rutgers, The State University of New Jersey	2014-05-31
NCT01389180	Behavioral Drug and HIV Risk Reduction Counseling With MMT in China	https://ClinicalTrials.gov/show/NCT01389180	Completed	Yale University	2016-06-30
NCT01380093	Abuse Potential of Orally Administered Crushed Embeda Compared to Crushed Controlled-Release Morphine and Placebo in Non-Dependent Recreational Opioid Users	https://ClinicalTrials.gov/show/NCT01380093	Completed	Pfizer	2011-05-31
NCT01377610	Improved Strategies for Outpatient Opioid Detoxification	https://ClinicalTrials.gov/show/NCT01377610	Completed	New York State Psychiatric Institute	2017-12-31
NCT01376570	Project FIRST - Financial Incentives to Reduce Substance Use and Improve Treatment	https://ClinicalTrials.gov/show/NCT01376570	Completed	Albert Einstein College of Medicine	2017-08-10
NCT01374763	A Comparison of PR Oxycodone/Naloxone and PR Oxycodone After Cardiac Surgery	https://ClinicalTrials.gov/show/NCT01374763	Completed	Tampere University Hospital	2011-12-31
NCT01344122	Medication-Assisted Treatment Implementation in Community Correctional Environments (MATICCE)	https://ClinicalTrials.gov/show/NCT01344122	Completed	Rhode Island Hospital	2013-09-30
NCT01334580	Cognitive-Behavioral Therapy for Pain and Opioid Dependence in Methadone Maintenance Treatment	https://ClinicalTrials.gov/show/NCT01334580	Completed	Yale University	2014-09-30
NCT04340622	Efficacy And Safety Of An Innovative Treatment Of Opiate Use Disorders	https://ClinicalTrials.gov/show/NCT04340622	Recruiting	MindLight, LLC	2020-12-15
NCT04272671	De-prescribing Program to Evaluate Falls in Older Adults	https://ClinicalTrials.gov/show/NCT04272671	Recruiting	University of North Carolina, Chapel Hill	2021-09-30
NCT04220489	Perioperative Ketamine in Opioid-Tolerant Patients Undergoing Lumbar Spine Surgery	https://ClinicalTrials.gov/show/NCT04220489	Recruiting	University of Pittsburgh	2020-06-30
NCT04189523	Does Early Administration of Ultrasound Guided Regional Anesthesia for Long Bone Fractures Effect Long Term Patient Opioid Usage	https://ClinicalTrials.gov/show/NCT04189523	Recruiting	Wayne State University	2020-06-30
NCT04080037	Assessing Opioid Care Practices Using CPV Patient Simulation Modules	https://ClinicalTrials.gov/show/NCT04080037	Completed	Qure Healthcare, LLC	2019-10-29
NCT04033562	The Analgesic Efficacy of Continuous Sub-fascial Bupivacaine Infusion and Lidocaine Patches in Post-cesarean Patients With Opiate Use Disorder: A Comparative Efficacy Analysis	https://ClinicalTrials.gov/show/NCT04033562	Recruiting	WellSpan Health	2021-09-01
NCT04018664	Oral Abuse Potential Study of Nalbuphine	https://ClinicalTrials.gov/show/NCT04018664	Completed	Trevi Therapeutics	2018-12-03
NCT04015115	Youth Opioid Recovery Support: Improving Care Systems	https://ClinicalTrials.gov/show/NCT04015115	Active, not recruiting	University of Maryland, Baltimore	2020-05-31
NCT03992079	A Multimodal Enhanced Recovery Program in Anorectal Surgery	https://ClinicalTrials.gov/show/NCT03992079	Recruiting	Columbia University	2020-07-31
NCT03971097	The Effect of Self-Forgiveness on Self-Stigma in Addiction.	https://ClinicalTrials.gov/show/NCT03971097	Completed	University of Pittsburgh	2019-12-01
NCT03950492	Feasibility of Deep Brain Stimulation as a Novel Treatment for Refractory Opioid Use Disorder	https://ClinicalTrials.gov/show/NCT03950492	Recruiting	West Virginia University	2020-12-30
NCT03949764	The Kentucky Viral Hepatitis Treatment Study	https://ClinicalTrials.gov/show/NCT03949764	Recruiting	University of Kentucky	2022-08-31
NCT03842137	tDCS to Decrease Opioid Relapse	https://ClinicalTrials.gov/show/NCT03842137	Recruiting	Butler Hospital	2023-12-31
NCT03838510	Repeated-dose Behavioral Intervention to Reduce Opioid Overdose	https://ClinicalTrials.gov/show/NCT03838510	Recruiting	San Francisco Department of Public Health	2022-12-31
NCT03837860	Reducing the Abuse of Opioids in Drug Users	https://ClinicalTrials.gov/show/NCT03837860	Recruiting	The University of Texas Health Science Center at San Antonio	2021-03-31
NCT03834025	Nudges and Incentives to Enhance the Opioid Treatment Workforce	https://ClinicalTrials.gov/show/NCT03834025	Active, not recruiting	University of North Carolina, Chapel Hill	2020-08-28
NCT03831113	Pharmacologically-based Strategies for Buprenorphine Treatment During Pregnancy	https://ClinicalTrials.gov/show/NCT03831113	Recruiting	University of Pittsburgh	2023-05-31
NCT03809143	Community Studies of Long Acting Buprenorphine (CoLAB)	https://ClinicalTrials.gov/show/NCT03809143	Active, not recruiting	The University of New South Wales	2020-11-01
NCT03798470	FAVOR Opioid Recovery Coaching Evaluation	https://ClinicalTrials.gov/show/NCT03798470	Completed	Prisma Health-Upstate	2018-12-31
NCT03791645	Evaluating The Efficacy Of A Mind-Body Intervention In Overcoming Opioid Addiction	https://ClinicalTrials.gov/show/NCT03791645	Recruiting	Ohio State University	2020-12-30
NCT03789214	Medical Management of Sleep Disturbance During Opioid Tapering	https://ClinicalTrials.gov/show/NCT03789214	Recruiting	Johns Hopkins University	2021-07-31
NCT03783702	Pain Control Following Sinus Surgery	https://ClinicalTrials.gov/show/NCT03783702	Recruiting	Stanford University	2019-10-01
NCT03779997	Trial of Adherence App for Buprenorphine Treatment (TAAB) Study	https://ClinicalTrials.gov/show/NCT03779997	Active, not recruiting	University of Washington	2020-05-15
NCT03773523	Neuromodulation and Cognitive Training in Opioid Use Disorder	https://ClinicalTrials.gov/show/NCT03773523	Recruiting	University of Minnesota	2021-10-31
NCT03769025	Remote Observed Dosing of Suboxone to Improve Clinical Practice	https://ClinicalTrials.gov/show/NCT03769025	Active, not recruiting	University of Pennsylvania	2022-12-31
NCT03681769	Developing Brain Stimulation as a Treatment for Chronic Pain in Opiate Dependent	https://ClinicalTrials.gov/show/NCT03681769	Recruiting	Medical University of South Carolina	2021-07-31
NCT03675386	Reducing Opioid Use for Chronic Pain Patients Following Surgery	https://ClinicalTrials.gov/show/NCT03675386	Recruiting	University Health Network, Toronto	2020-09-30
NCT03662529	Neurobehavioral Measurement of Substance Users in Outpatient Treatment Setting	https://ClinicalTrials.gov/show/NCT03662529	Completed	Hunter Holmes Mcguire Veteran Affairs Medical Center	2018-01-08
NCT03647774	Long Acting Naltrexone for Opioid Addiction: Focus on Sustained Abstinence and Recovery	https://ClinicalTrials.gov/show/NCT03647774	Recruiting	University Hospital, Akershus	2023-08-31
NCT03604159	XRB vs. SLB in Jail and at Re-entry: Pilot, Proof of Concept	https://ClinicalTrials.gov/show/NCT03604159	Recruiting	NYU Langone Health	2020-06-30
NCT03576781	Developing rTMS Treatment Strategies for Pain in Opiate Dependence	https://ClinicalTrials.gov/show/NCT03576781	Completed	Medical University of South Carolina	2019-11-12
NCT03575273	The Impact of Methadone Maintenance Therapy on Food Reward Processing in Opioid Dependence	https://ClinicalTrials.gov/show/NCT03575273	Active, not recruiting	Johns Hopkins University	2019-12-01
NCT03567356	Treatment of Opioid Use: Medication Adherence Therapy	https://ClinicalTrials.gov/show/NCT03567356	Recruiting	Potomac Health Foundations	2020-09-30
NCT03549312	Switch to Genvoya Followed by HCV Therapy With Epclusa Followed by Simplification of HIV Therapy With Biktarvy in Patients With HIV-HCV Co-Infected Subjects on Opioid Substitution Therapy	https://ClinicalTrials.gov/show/NCT03549312	Recruiting	Saskatchewan Health Authority - Regina Area	2020-07-21
NCT03526380	The OPT-IN Project	https://ClinicalTrials.gov/show/NCT03526380	Active, not recruiting	University of Michigan	2020-06-30
NCT03521960	Buspirone for Opioid Tapering	https://ClinicalTrials.gov/show/NCT03521960	Recruiting	Johns Hopkins University	2020-05-30
NCT03475862	Nasal Human Abuse Potential of PTI-821	https://ClinicalTrials.gov/show/NCT03475862	Completed	PainT	2017-07-31
NCT03447743	Re-entry XR-NTX for Rural Women With Opioid Use Disorder	https://ClinicalTrials.gov/show/NCT03447743	Recruiting	University of Kentucky	2021-03-31
NCT03411265	RETAIN: Retaining Opioid Users Entering Medication Assisted Treatment and Encouraging HCV/HIV Testing	https://ClinicalTrials.gov/show/NCT03411265	Completed	University of Cincinnati	2018-09-06
NCT01262261	Re-Treatment Study of Probuphine in Opioid Addiction	https://ClinicalTrials.gov/show/NCT01262261	Completed	Titan Pharmaceuticals	2011-11-30
NCT01262092	Effects of Gabapentin Versus Placebo on Buprenorphine Detoxification of Opioid-dependent Individuals	https://ClinicalTrials.gov/show/NCT01262092	Completed	University of Arkansas	2011-12-31
NCT01246401	Naltrexone for Opioid Dependent Released Human Immunodeficiency Virus Positive (HIV+) Criminal Justice Populations	https://ClinicalTrials.gov/show/NCT01246401	Completed	Yale University	2016-03-31
NCT01218984	ALK21-004: Single-dose Opiate Challenge of Medisorb® Naltrexone (VIVITROL®) in Adults Who Use Opioids	https://ClinicalTrials.gov/show/NCT01218984	Completed	Alkermes, Inc.	2003-05-31
NCT01188421	Medications Development for Drug Abuse Disorders	https://ClinicalTrials.gov/show/NCT01188421	Completed	Johns Hopkins University	2015-06-30
NCT01182402	Electronic Compliance Monitoring in Opioid Substitution Treatment	https://ClinicalTrials.gov/show/NCT01182402	Completed	Kuopio University Hospital	2011-02-28
NCT01180647	Extended-Release Naltrexone for Opioid Relapse Prevention Following Release From Jail	https://ClinicalTrials.gov/show/NCT01180647	Completed	NYU Langone Health	2013-07-31
NCT01136356	A Within Subject Comparison of Opioid Withdrawal in Opioid Dependent Individuals	https://ClinicalTrials.gov/show/NCT01136356	Completed	Johns Hopkins University	2012-03-31
NCT01114308	A Six-Month Randomized Controlled Trial (RCT) of Probuphine Safety and Efficacy in Opioid Addiction	https://ClinicalTrials.gov/show/NCT01114308	Completed	Titan Pharmaceuticals	2011-05-31
NCT01082679	Treatment for Opioid Dependent Offenders	https://ClinicalTrials.gov/show/NCT01082679	Completed	University of Wisconsin, Madison	2011-03-31
NCT01052662	Memantine-enhanced Buprenorphine Treatment for Opioid-dependent Young Adults	https://ClinicalTrials.gov/show/NCT01052662	Completed	University of Massachusetts, Worcester	2013-06-30
NCT01045278	Hepatitis C in a Cohort of Patients With Maintenance Therapy for Opiate Dependence - Prevalence, Severity and Outcome of Antiviral Therapy	https://ClinicalTrials.gov/show/NCT01045278	Completed	Region Skane	2013-09-30
NCT01030406	Study of the Relative Abuse Potential of Acurox Tablets in Non-Dependent Recreational Opioid Users	https://ClinicalTrials.gov/show/NCT01030406	Completed	Acura Pharmaceuticals Inc.	2010-02-28
NCT01024335	Dronabinol Naltrexone Treatment for Opioid Dependence	https://ClinicalTrials.gov/show/NCT01024335	Completed	New York State Psychiatric Institute	2012-12-31
NCT01004393	Methylnaltrexone for Opioid-induced Constipation in Cancer Patients	https://ClinicalTrials.gov/show/NCT01004393	Completed	University of Vermont	2013-12-31
NCT00999544	Aprepitant Effects on Oxycodone Response	https://ClinicalTrials.gov/show/NCT00999544	Completed	University of Kentucky	2011-04-30
NCT00992095	Bioequivalency Study of Buprenorphine Hydrochloride 8 mg Tablet Under Fasted Conditions	https://ClinicalTrials.gov/show/NCT00992095	Completed	West-Ward Pharmaceutical	2006-09-30
NCT00987961	Linking Hospitalized Injection Drug Users to Buprenorphine	https://ClinicalTrials.gov/show/NCT00987961	Completed	Butler Hospital	2014-03-31
NCT00929253	Efficacy of Computer Delivered Community Reinforcement Approach (CRA) (Bup II)	https://ClinicalTrials.gov/show/NCT00929253	Completed	Virginia Polytechnic Institute and State University	2010-04-30
NCT00913770	Models of Screening, Brief Intervention With a Facilitated Referral to Treatment (SBIRT) for Opioid Patients in the Emergency Department	https://ClinicalTrials.gov/show/NCT00913770	Completed	Yale University	2013-08-31
NCT00901875	Multicentre Trial of Suboxone in Opiate-dependent Subjects in Taiwan	https://ClinicalTrials.gov/show/NCT00901875	Completed	Indivior Inc.	2009-11-30
NCT00879996	Buprenorphine and Methadone for Opioid Dependent Chronic Pain Patients	https://ClinicalTrials.gov/show/NCT00879996	Completed	State University of New York at Buffalo	2011-10-31
NCT00842036	CRAFT Behavior Therapy: Treatment Entry Component	https://ClinicalTrials.gov/show/NCT00842036	Completed	Treatment Research Institute	2009-12-31
NCT03241771	Impact of Direct Outreach to Expand Access to Naloxone in the Context of Standing Orders	https://ClinicalTrials.gov/show/NCT03241771	Active, not recruiting	Kaiser Permanente	2018-08-14
NCT00834080	ALK21-021: A Safety Study of Medisorb® Naltrexone (VIVITROL®) Administered to Health Care Professionals	https://ClinicalTrials.gov/show/NCT00834080	Completed	Alkermes, Inc.	2012-05-31
NCT00829777	Safety Study of Intravenous 6β-Naltrexol (AIKO-150) in Opioid-Dependent Subjects	https://ClinicalTrials.gov/show/NCT00829777	Completed	California Pacific Medical Center Research Institute	2009-09-30
NCT01550341	HIV, Buprenorphine, and the Criminal Justice System	https://ClinicalTrials.gov/show/NCT01550341	Completed	Yale University	2015-11-30
NCT01436474	Pilot Study of Varenicline to Treat Opioid Dependence	https://ClinicalTrials.gov/show/NCT01436474	Completed	Mayo Clinic	2012-09-30
NCT01389167	Naltrexone and Behavioral Drug and HIV Risk Reduction Counseling in Russia	https://ClinicalTrials.gov/show/NCT01389167	Completed	Yale University	2016-09-30
NCT04156802	Project Relief: Developing Brain Stimulation as a Treatment for Chronic Pain	https://ClinicalTrials.gov/show/NCT04156802	Recruiting	Wake Forest University Health Sciences	2021-12-31
NCT03891628	Modified ABC: A Home-based Parenting Program for Opioid-dependent Mothers and Their Infants	https://ClinicalTrials.gov/show/NCT03891628	Recruiting	University of Delaware	2025-03-31
NCT03538444	Repetitive Transcranial Magnetic Stimulation for Opiate Use Disorder	https://ClinicalTrials.gov/show/NCT03538444	Recruiting	Medical University of South Carolina	2021-06-01
NCT03155906	Integrated Treatment of Hepatitis C Virus Infection	https://ClinicalTrials.gov/show/NCT03155906	Active, not recruiting	Haukeland University Hospital	2020-05-08
NCT03022890	Study of Yoga vs. Health Education for Chronic Pain in Persons Receiving Opioid Agonist Therapy	https://ClinicalTrials.gov/show/NCT03022890	Completed	Butler Hospital	2018-11-16
NCT02992938	Administration of Acetazolamide to Prevent Remifentanil Induced Hyperalgesia	https://ClinicalTrials.gov/show/NCT02992938	Completed	University of Chile	2018-09-28
NCT02617628	Outcomes of Opioid Addicted Prisoners With Extended-Release Injectable Naltrexone	https://ClinicalTrials.gov/show/NCT02617628	Completed	University of Pennsylvania	2018-12-31
NCT02737696	Computer-based Prescription Opioid Abuse Prevention for Adolescents	https://ClinicalTrials.gov/show/NCT02737696	Completed	Dartmouth-Hitchcock Medical Center	2018-03-18
NCT03833245	Optimizing Pregnancy and Treatment Interventions for Moms 2.0	https://ClinicalTrials.gov/show/NCT03833245	Recruiting	University of Utah	2022-02-28
NCT03610672	Mobile Intervention for Young Opioid Users	https://ClinicalTrials.gov/show/NCT03610672	Recruiting	National Development and Research Institutes, Inc.	2019-11-28
NCT03527485	Imaging Synaptic Density in Cocaine and Opiate Addiction In Vivo Using 11UCB-J PET	https://ClinicalTrials.gov/show/NCT03527485	Active, not recruiting	Yale University	2023-12-31
NCT00781898	Treatment Study Using Depot Naltrexone (1/6) Philadelphia Coord/Data Mgmt Site	https://ClinicalTrials.gov/show/NCT00781898	Completed	University of Pennsylvania	2015-08-31
NCT00780702	Aripiprazole for Prevention of Relapse to Cocaine Use in Methadone-Maintenance Patients	https://ClinicalTrials.gov/show/NCT00780702	Completed	National Institutes of Health Clinical Center (CC)	2013-04-16
NCT00763958	Relapse Prevention to Reduce HIV Among Women Prisoners	https://ClinicalTrials.gov/show/NCT00763958	Completed	University of Alabama at Birmingham	2009-09-30
NCT00757744	Behavioral Drug and HIV Risk Reduction Counseling in Methadone Patients in China	https://ClinicalTrials.gov/show/NCT00757744	Completed	Yale University	2010-01-31
NCT00756990	Depot Naltrexone Treatment of Opioid Dependent Parolees	https://ClinicalTrials.gov/show/NCT00756990	Completed	University of Pennsylvania	2009-03-31
NCT00734461	Study to Evaluate the Subjective Effects of PTI-801 in Non-Physically Dependent Subjects With a History of Drug Abuse	https://ClinicalTrials.gov/show/NCT00734461	Completed	PainT	2009-03-31
NCT00733239	Drug Discrimination in Methadone-Maintained Humans Study 2	https://ClinicalTrials.gov/show/NCT00733239	Completed	University of Arkansas	2010-10-31
NCT00727675	Chronic Pain and Opioid Dependence Assessment and Treatment	https://ClinicalTrials.gov/show/NCT00727675	Completed	Yale University	2014-07-31
NCT00723177	Phase IIa Study of AV411, a Glial Activation Inhibitor, for Opioid Withdrawal	https://ClinicalTrials.gov/show/NCT00723177	Completed	New York State Psychiatric Institute	2010-04-30
NCT00719095	Effective Treatment for Prescription Opioid Abuse	https://ClinicalTrials.gov/show/NCT00719095	Completed	University of Vermont Medical Center	2010-03-31
NCT00718835	Incentive-based Smoking Cessation for Methadone Patients	https://ClinicalTrials.gov/show/NCT00718835	Completed	University of Vermont Medical Center	2013-06-30
NCT00712036	Entry Into Comprehensive Methadone Treatment Via Interim Maintenance	https://ClinicalTrials.gov/show/NCT00712036	Completed	Friends Research Institute, Inc.	2011-01-31
NCT00710385	Abuse Liability of Suboxone Versus Subutex	https://ClinicalTrials.gov/show/NCT00710385	Completed	New York State Psychiatric Institute	2008-08-31
NCT00699010	Study of the Abuse Liability of Oxycodone HCl/Niacin in Subjects With a History of Opioid Abuse	https://ClinicalTrials.gov/show/NCT00699010	Completed	Acura Pharmaceuticals Inc.	2008-08-31
NCT00684788	Employment-Based Depot Naltrexone Clinical Trial	https://ClinicalTrials.gov/show/NCT00684788	Completed	Johns Hopkins University	2009-05-31
NCT00684775	Employment-Based Depot Naltrexone Clinical Trial II	https://ClinicalTrials.gov/show/NCT00684775	Completed	Johns Hopkins University	2010-04-30
NCT00684554	Buprenorphine Maintenance Treatment of Opioid Dependence in Primary Care: A Randomized Clinical Trial	https://ClinicalTrials.gov/show/NCT00684554	Completed	New York State Psychiatric Institute	2008-08-31
NCT00684073	Preference for Subutex® (Buprenorphine) Versus Suboxone® (Buprenorphine/Naloxone) in Opioid Dependent Patients on Subutex® (Study P05094)(COMPLETED)	https://ClinicalTrials.gov/show/NCT00684073	Completed	Indivior Inc.	2007-12-31
NCT00678418	ALK21-013: Efficacy and Safety of Medisorb® Naltrexone (VIVITROL®) in Adults With Opioid Dependence	https://ClinicalTrials.gov/show/NCT00678418	Completed	Alkermes, Inc.	2009-10-31
NCT00640835	Safety and Tolerability of Buprenorphine/Naloxone Film Strips	https://ClinicalTrials.gov/show/NCT00640835	Completed	Indivior Inc.	2008-10-31
NCT00637000	Induction of Opioid-Dependent Individuals Onto Buprenorphine and Buprenorphine/Naloxone	https://ClinicalTrials.gov/show/NCT00637000	Completed	Indivior Inc.	2008-09-30
NCT00633243	Effective Treatment of Hepatitis C in Substance Users	https://ClinicalTrials.gov/show/NCT00633243	Completed	Yale University	2011-09-30
NCT00630201	Extension to Safety and Efficacy of Probuphine in the Treatment of Opioid Dependence	https://ClinicalTrials.gov/show/NCT00630201	Completed	Titan Pharmaceuticals	2009-02-28
NCT00622596	Prospective Cohort of Opiate Dependent Patients on Buprenorphine/Naloxone for Maintenance	https://ClinicalTrials.gov/show/NCT00622596	Completed	Yale University	2008-09-30
NCT00605033	A Randomized Acceptability and Safety Study of the Transfer From Subutex to Suboxone in Opioid- Dependent Subjects (Study P04843)(COMPLETED)	https://ClinicalTrials.gov/show/NCT00605033	Completed	Indivior Inc.	2009-04-30
NCT00604188	A Randomized Acceptability and Safety Study of Suboxone Induction in Heroin Users (P05042)(COMPLETED)	https://ClinicalTrials.gov/show/NCT00604188	Completed	Merck Sharp & Dohme Corp.	2009-12-10
NCT00595764	Counseling for Primary Care Office-based Buprenorphine	https://ClinicalTrials.gov/show/NCT00595764	Completed	Yale University	2011-02-28
NCT00593125	Levetiracetam (Keppra) Tolerability in Cocaine Abusing Methadone-maintained Patients.	https://ClinicalTrials.gov/show/NCT00593125	Completed	National Institute on Drug Abuse (NIDA)	2007-08-31
NCT00591617	Optimizing Outcomes Using Suboxone for Opiate Dependence	https://ClinicalTrials.gov/show/NCT00591617	Completed	University of California, Los Angeles	2012-01-31
NCT00580827	Clinical Efficacy of Disulfiram in LAAM-Maintained Cocaine Abusers	https://ClinicalTrials.gov/show/NCT00580827	Completed	Yale University	2004-03-31
NCT00577408	Behavioral Naltrexone Therapy for Promoting Adherence to Oral Naltrexone vs Extended Release Injectable Depot Naltrexone	https://ClinicalTrials.gov/show/NCT00577408	Completed	New York State Psychiatric Institute	2011-08-31
NCT00566969	Cocaine Withdrawal and Pharmacotherapy Response	https://ClinicalTrials.gov/show/NCT00566969	Completed	Yale University	2012-12-31
NCT00555425	Buprenorphine Maintenance vs. Detoxification in Prescription Opioid Dependence	https://ClinicalTrials.gov/show/NCT00555425	Completed	Yale University	2013-05-31
NCT00548275	Reducing Sex-Related HIV Risk Behaviors in Patients Receiving Treatment for Opioid Dependence	https://ClinicalTrials.gov/show/NCT00548275	Completed	Yale University	2011-06-30
NCT00521157	Naltrexone Implants as an Aid in Preventing Relapse Following Inpatient Treatment for Opioid Addiction	https://ClinicalTrials.gov/show/NCT00521157	Completed	University of Oslo	2008-06-30
NCT00499746	The Discriminative Effects of Tramadol in Humans	https://ClinicalTrials.gov/show/NCT00499746	Completed	National Institute on Drug Abuse (NIDA)	2010-04-30
NCT00476242	Memantine as a Supplement to Naltrexone in Treating Heroin Dependence	https://ClinicalTrials.gov/show/NCT00476242	Completed	New York State Psychiatric Institute	2011-08-31
NCT00475878	SSRI and Buprenorphine	https://ClinicalTrials.gov/show/NCT00475878	Completed	Butler Hospital	2009-09-30
NCT00460239	Buprenorphine’s Dose Response Curve	https://ClinicalTrials.gov/show/NCT00460239	Completed	Johns Hopkins University	2009-07-31
NCT00447564	Safety and Efficacy of Probuphine in the Treatment of Opioid Dependence	https://ClinicalTrials.gov/show/NCT00447564	Completed	Titan Pharmaceuticals	2008-07-31
NCT00439036	Acceptance Therapy During Methadone Detoxification	https://ClinicalTrials.gov/show/NCT00439036	Completed	The University of Texas Health Science Center, Houston	2010-08-31
NCT00420771	Gabapentin Treatment of Benzodiazepine Abuse in Methadone Maintenance Patients	https://ClinicalTrials.gov/show/NCT00420771	Completed	New York State Psychiatric Institute	2011-01-31
NCT00367302	Buprenorphine Maintenance for Opioid-Addicted Persons in Jail and Post-Release	https://ClinicalTrials.gov/show/NCT00367302	Completed	National Development and Research Institutes, Inc.	2008-01-31
NCT00406484	Brief Introductory Therapy for Opioid Dependence	https://ClinicalTrials.gov/show/NCT00406484	Completed	Yale University	2009-09-30
NCT00383045	HIV Risk Reduction and Drug Abuse Treatment in Malaysia	https://ClinicalTrials.gov/show/NCT00383045	Completed	Yale University	NA
NCT00367874	Treatment of Polydrug-Using Opiate Dependents During Withdrawal	https://ClinicalTrials.gov/show/NCT00367874	Completed	Sorlandet Hospital HF	NA
NCT00351026	Methadone Maintenance & HIV Risk in Ukraine	https://ClinicalTrials.gov/show/NCT00351026	Completed	University of Pennsylvania	2010-10-31
NCT00348868	Buprenorphine HIV Care Integration Project	https://ClinicalTrials.gov/show/NCT00348868	Completed	University of Miami	2007-12-31
NCT00344812	Opioid Maintenance Medications Comparison Study	https://ClinicalTrials.gov/show/NCT00344812	Completed	Johns Hopkins University	NA
NCT00332228	Behavioral Naltrexone Therapy: A Novel Treatment for Heroin Dependence	https://ClinicalTrials.gov/show/NCT00332228	Completed	New York State Psychiatric Institute	2007-12-31
NCT00316277	Prescription Opioid Addiction Treatment Study (POATS)	https://ClinicalTrials.gov/show/NCT00316277	Completed	Mclean Hospital	2009-07-31
NCT00301210	Assessment of Tramadol as a Treatment for Opioid Addiction	https://ClinicalTrials.gov/show/NCT00301210	Completed	Johns Hopkins University	2007-10-31
NCT00300794	Effects of Ketamine On Precipitated Opioid Withdrawal Under General Anaesthesia	https://ClinicalTrials.gov/show/NCT00300794	Completed	Vilnius University	NA
NCT00295308	Clonidine for Relapse Prevention in Buprenorphine-Maintenance Patients	https://ClinicalTrials.gov/show/NCT00295308	Completed	National Institutes of Health Clinical Center (CC)	NA
NCT00292123	Combined Behavioral and Pharmacologic Treatment of Polydrug Abuse	https://ClinicalTrials.gov/show/NCT00292123	Completed	National Institute on Drug Abuse (NIDA)	2006-06-30
NCT00268814	The German Project of Heroin Assisted Treatment of Opiate Dependent Patients	https://ClinicalTrials.gov/show/NCT00268814	Completed	Universitätsklinikum Hamburg-Eppendorf	2003-12-31
NCT00271219	RCT Comparing Methadone and Buprenorphine in Pregnant Women	https://ClinicalTrials.gov/show/NCT00271219	Completed	Johns Hopkins University	2009-08-31
NCT00263458	Integrating Buprenorphine Into the SFGH AIDS Program	https://ClinicalTrials.gov/show/NCT00263458	Completed	University of California, San Francisco	2009-06-30
NCT00253890	Insomnia and Drug Relapse Risk	https://ClinicalTrials.gov/show/NCT00253890	Completed	Butler Hospital	2010-05-31
NCT00249587	Medication Adherence Therapy for Opioid Abusing Pain Patients	https://ClinicalTrials.gov/show/NCT00249587	Completed	National Institute on Drug Abuse (NIDA)	2005-09-30
NCT00249470	The Therapeutic Workplace Initiation Study	https://ClinicalTrials.gov/show/NCT00249470	Completed	Johns Hopkins University	2004-05-31
NCT00249457	Employment-based Reinforcement to Motivate Drug Abstinence in the Treatment of Drug Addiction. - 2	https://ClinicalTrials.gov/show/NCT00249457	Completed	Johns Hopkins University	2006-01-31
NCT00241943	A Video-Based HCV Curriculum for Active Injection Drug Users	https://ClinicalTrials.gov/show/NCT00241943	Completed	Organization to Achieve Solutions in Substance Abuse (OASIS)	2007-08-31
NCT00241917	A Video-Based HCV Curriculum for Drug Users	https://ClinicalTrials.gov/show/NCT00241917	Completed	Organization to Achieve Solutions in Substance Abuse (OASIS)	2007-05-31
NCT00238914	Opiate Dependence: Combined Naltrexone/Behavior Therapy - 1	https://ClinicalTrials.gov/show/NCT00238914	Completed	New York State Psychiatric Institute	2002-07-31
NCT00235729	Lofexidine for Inpatient Opiate Detox	https://ClinicalTrials.gov/show/NCT00235729	Completed	VA Office of Research and Development	2007-10-31
NCT00218608	Disulfiram for Treating Cocaine Dependence in Individuals Maintained on Methadone	https://ClinicalTrials.gov/show/NCT00218608	Completed	University of Arkansas	2007-01-31
NCT00218426	Addiction Treatment in Russia: Oral vs. Naltrexone Implant	https://ClinicalTrials.gov/show/NCT00218426	Completed	University of Pennsylvania	2009-06-30
NCT00218374	Dextromethorphan, Gabapentin, and Oxycodone to Treat Opioid-Induced Hyperalgesia	https://ClinicalTrials.gov/show/NCT00218374	Completed	National Institute on Drug Abuse (NIDA)	2007-06-30
NCT00218101	Buprenorphine as a Treatment for Individuals Dependent on Analgesic Opioids	https://ClinicalTrials.gov/show/NCT00218101	Completed	National Institute on Drug Abuse (NIDA)	NA
NCT00204243	Naltrexone Implants vs. MMT Among Inmates in the Norwegian Correctional Services	https://ClinicalTrials.gov/show/NCT00204243	Completed	University of Oslo	2008-02-29
NCT00175357	NAOMI: A Study to Compare Medically-prescribed Heroin With Oral Methadone in Chronic Opiate Addiction	https://ClinicalTrials.gov/show/NCT00175357	Completed	University of British Columbia	2007-04-30
NCT00158288	The Efficacy of Methadyl Acetate (LAAM) and Contingency Management Procedures for Treating Dual Opioid and Cocaine Abuse - 1	https://ClinicalTrials.gov/show/NCT00158288	Completed	National Institute on Drug Abuse (NIDA)	NA
NCT00158236	Abuse Potential of Buprenorphine and Naloxone in Non-Dependent Opioid Users	https://ClinicalTrials.gov/show/NCT00158236	Completed	National Institute on Drug Abuse (NIDA)	NA
NCT00158184	Prescription Opioid Effects in Abusers Versus Non-Abusers	https://ClinicalTrials.gov/show/NCT00158184	Completed	New York State Psychiatric Institute	2009-06-30
NCT00149669	Employment-based Reinforcement of Naltrexone Ingestion and Abstinence	https://ClinicalTrials.gov/show/NCT00149669	Completed	Johns Hopkins University	2010-12-31
NCT00149630	Pharmacogenetics of Disulfiram for Cocaine	https://ClinicalTrials.gov/show/NCT00149630	Completed	Baylor College of Medicine	2009-12-31
NCT00147784	HEPMET-1: Evaluate the Feasibility, Mental Sideeffects and the Efficacy of Hepatitis C Treatment in a MMT Group.	https://ClinicalTrials.gov/show/NCT00147784	Completed	Sorlandet Hospital HF	2007-06-30
NCT00142935	Effectiveness of Opiate Replacement Therapy Administered Prior to Release From a Correctional Facility - 1	https://ClinicalTrials.gov/show/NCT00142935	Completed	The Miriam Hospital	2009-12-31
NCT00142909	Effectiveness of Lofexidine to Prevent Stress-Related Opiate Relapse During Naltrexone Treatment - 1	https://ClinicalTrials.gov/show/NCT00142909	Completed	Yale University	2009-01-31
NCT00142896	Tramadol to Reduce Opioid Withdrawal Symptoms	https://ClinicalTrials.gov/show/NCT00142896	Completed	National Institute on Drug Abuse (NIDA)	2005-12-31
NCT00142779	Fluoxetine to Reduce Cocaine Use in Cocaine and Opioid Addicts	https://ClinicalTrials.gov/show/NCT00142779	Completed	National Institute on Drug Abuse (NIDA)	2006-01-31
NCT00135759	Addition of Naltrexone to Methadone Taper	https://ClinicalTrials.gov/show/NCT00135759	Completed	National Institute on Drug Abuse (NIDA)	NA
NCT00134914	Effects of Buprenorphine/Naloxone Administered in Different Ways For Treating Opioid Dependence	https://ClinicalTrials.gov/show/NCT00134914	Completed	National Institute on Drug Abuse (NIDA)	1998-04-30
NCT00134888	Blockade Efficacy of Buprenorphine/Naloxone For Opioid Dependence	https://ClinicalTrials.gov/show/NCT00134888	Completed	National Institute on Drug Abuse (NIDA)	NA
NCT00130819	Comparison of HIV Clinic-based Treatment With Buprenorphine Versus Referred Care in Heroin-dependent Participants	https://ClinicalTrials.gov/show/NCT00130819	Completed	Johns Hopkins University	2009-04-30
NCT00129298	Effectiveness of Tiagabine for Cocaine Dependence in Methadone-Maintained Individuals - 1	https://ClinicalTrials.gov/show/NCT00129298	Completed	National Institute on Drug Abuse (NIDA)	NA
NCT00798538	Integration of Buprenorphine Into HIV Clinical Settings - Primary Care Model (PCM)	https://ClinicalTrials.gov/show/NCT00798538	Completed	Yale University	2010-08-31
NCT00125515	Memantine and Naltrexone Treatment for Opioid Dependence	https://ClinicalTrials.gov/show/NCT00125515	Completed	New York State Psychiatric Institute	2008-08-31
NCT00117741	Evaluation of DBT Compared to Drug Counseling for Opiate Addicts	https://ClinicalTrials.gov/show/NCT00117741	Completed	University of Washington	2008-10-31
NCT00078130	Buprenorphine/Naloxone - Facilitated Rehabilitation for Opioid Dependent Adolescents - 1	https://ClinicalTrials.gov/show/NCT00078130	Completed	National Institute on Drug Abuse (NIDA)	2006-01-31
NCT00078117	Suboxone: (Buprenorphine/Naloxone) Comparison of Two Taper Schedules - 1	https://ClinicalTrials.gov/show/NCT00078117	Completed	National Institute on Drug Abuse (NIDA)	2005-05-31
NCT00061100	HIV Counseling Intervention for Methadone-Maintained Patients - 2	https://ClinicalTrials.gov/show/NCT00061100	Completed	New York State Psychiatric Institute	2003-10-31
NCT00061087	Treatment of Adult Attention Deficit Hyperactivity Disorder (ADHD) in Methadone Patients - 1	https://ClinicalTrials.gov/show/NCT00061087	Completed	New York State Psychiatric Institute	2004-10-31
NCT00032942	Lofexidine for Opiate Withdrawal - 1	https://ClinicalTrials.gov/show/NCT00032942	Completed	National Institute on Drug Abuse (NIDA)	2004-10-31
NCT00018226	Effect Of Case Management Following Discharge From Methadone Treatment	https://ClinicalTrials.gov/show/NCT00018226	Completed	VA Office of Research and Development	NA
NCT00015340	Buprenorphine/Naloxone in the Treatment of Heroin Dependence - 14	https://ClinicalTrials.gov/show/NCT00015340	Completed	National Institute on Drug Abuse (NIDA)	2001-08-31
NCT00015288	Buprenorphine and Naloxone Combination Study - 10	https://ClinicalTrials.gov/show/NCT00015288	Completed	National Institute on Drug Abuse (NIDA)	NA
NCT00007527	Determine the Safety of a Sublingual Tablet Formulation of Buprenorphine and Naloxone by Extending the Combination Tablet Availability to Physicians in Office-Based Practice	https://ClinicalTrials.gov/show/NCT00007527	Completed	VA Office of Research and Development	NA
NCT00000254	Isoflurane at Subanesthetic Concentrations - 6	https://ClinicalTrials.gov/show/NCT00000254	Completed	University of Chicago	1995-09-30
NCT00218127	Treatment of Opioid/Heroin Dependence: Comparison of Three Medication Dosing Regimens	https://ClinicalTrials.gov/show/NCT00218127	Completed	National Institute on Drug Abuse (NIDA)	2005-07-31
NCT00000358	Evaluation of Lofexidine for Treatment of Opioid Withdrawal - 7	https://ClinicalTrials.gov/show/NCT00000358	Completed	National Institute on Drug Abuse (NIDA)	NA
NCT00000357	Buprenorphine Maintenance for Opiate Dependence - 6	https://ClinicalTrials.gov/show/NCT00000357	Completed	National Institute on Drug Abuse (NIDA)	1993-08-31
NCT00000356	Evaluation of L-alpha-acetylmethadol (LAAM) in Methadone Patients - 5	https://ClinicalTrials.gov/show/NCT00000356	Completed	National Institute on Drug Abuse (NIDA)	1992-08-31
NCT00000355	Effects of Buprenorphine and Naloxone in Opiate Addicts - 4	https://ClinicalTrials.gov/show/NCT00000355	Completed	National Institute on Drug Abuse (NIDA)	1996-01-31
NCT00000354	Evaluation of Lofexidine for Treatment of Opioid Withdrawal - 3	https://ClinicalTrials.gov/show/NCT00000354	Completed	National Institute on Drug Abuse (NIDA)	1997-09-30
NCT00000353	Trial of Buprenorphine/Naloxone for Opiate Dependence - 2	https://ClinicalTrials.gov/show/NCT00000353	Completed	National Institute on Drug Abuse (NIDA)	1997-09-30
NCT00000352	Effects of Dextromethorphan on Opioid Tolerance in Methadone Patients - 1	https://ClinicalTrials.gov/show/NCT00000352	Completed	National Institute on Drug Abuse (NIDA)	1998-02-28
NCT00000345	Evaluation of Lofexidine for Treatment of Opiate Withdrawal - 10	https://ClinicalTrials.gov/show/NCT00000345	Completed	National Institute on Drug Abuse (NIDA)	NA
NCT00000344	Buprenorphine/Naloxone for Treatment of Opiate Dependence - 9	https://ClinicalTrials.gov/show/NCT00000344	Completed	National Institute on Drug Abuse (NIDA)	NA
NCT00000341	Evaluation of Liquid vs. Tablet Buprenorphine - 6	https://ClinicalTrials.gov/show/NCT00000341	Completed	National Institute on Drug Abuse (NIDA)	NA
NCT00000335	Activity Monitoring Assessment of Opiate Withdrawal - 4	https://ClinicalTrials.gov/show/NCT00000335	Completed	National Institute on Drug Abuse (NIDA)	1996-03-20
NCT00000334	Comparison of Buprenorphine and Methadone - 3	https://ClinicalTrials.gov/show/NCT00000334	Completed	National Institute on Drug Abuse (NIDA)	2004-11-01
NCT00000320	Buprenorphine Formulation Comparison: Sublingual Tablet vs. Solution - 1	https://ClinicalTrials.gov/show/NCT00000320	Completed	National Institute on Drug Abuse (NIDA)	1999-08-31
NCT00000318	Buprenorphine Maintenance Dose Schedule and Treatment Setting - 1	https://ClinicalTrials.gov/show/NCT00000318	Completed	National Institute on Drug Abuse (NIDA)	2004-03-31
NCT00000311	Combining Behavioral Treatment With Agonist Maintenance - 1	https://ClinicalTrials.gov/show/NCT00000311	Completed	Yale University	1999-02-28
NCT00000306	Dextroamphetamine as Adjunct in Cocaine/Opiate Dependent Patients - 3	https://ClinicalTrials.gov/show/NCT00000306	Completed	National Institute on Drug Abuse (NIDA)	NA
NCT00000300	Feasibility Study of Take-Home LAAM Medication - 3	https://ClinicalTrials.gov/show/NCT00000300	Completed	University of California, Los Angeles	NA
NCT00000299	Rapid Opiate Detoxification and Naltrexone Induction Using Buprenorphine - 2	https://ClinicalTrials.gov/show/NCT00000299	Completed	University of California, Los Angeles	2009-11-30
NCT00000298	Buprenorphine Combination Tablet Feasibility - 1	https://ClinicalTrials.gov/show/NCT00000298	Completed	National Institute on Drug Abuse (NIDA)	NA
NCT00000279	Novel Medications for Opiate Detoxification - 4	https://ClinicalTrials.gov/show/NCT00000279	Completed	Yale University	1999-08-31
NCT00000273	A Laboratory Model for Heroin Abuse Medications - 8	https://ClinicalTrials.gov/show/NCT00000273	Completed	New York State Psychiatric Institute	2005-11-30
NCT00000264	Subjective/Psychomotor/ Effects of Combined Alcohol & Nitrous Oxide - 16	https://ClinicalTrials.gov/show/NCT00000264	Completed	University of Chicago	1999-10-31
NCT00000263	Effects of Combined Alcohol and Nitrous Oxide Intake - 15	https://ClinicalTrials.gov/show/NCT00000263	Completed	University of Chicago	1998-10-31
NCT00000262	Effects of Combined Sevoflurane and Nitrous Oxide Inhalation - 14	https://ClinicalTrials.gov/show/NCT00000262	Completed	University of Chicago	1999-02-28
NCT00000261	Effects of Alcohol History on Effects of Sevoflurane and Nitrous Oxide - 13	https://ClinicalTrials.gov/show/NCT00000261	Completed	University of Chicago	1998-10-31
NCT00000260	Effects of Behavioral Contingencies on Effects of Nitrous Oxide - 12	https://ClinicalTrials.gov/show/NCT00000260	Completed	University of Chicago	1998-01-31
NCT00000259	Sevoflurane vs Nitrous Oxide Inhalation at Subanesthetic Concentrations - 11	https://ClinicalTrials.gov/show/NCT00000259	Completed	University of Chicago	1997-11-30
NCT00000258	Role of Instructions in Nitrous Oxide Effects and Choice - 10	https://ClinicalTrials.gov/show/NCT00000258	Completed	University of Chicago	1997-11-30
NCT00000257	Effects of Alcohol History on Effects of Nitrous Oxide - 9	https://ClinicalTrials.gov/show/NCT00000257	Completed	University of Chicago	1997-04-30
NCT00000256	Reinforcing Effects of Brief Exposures to Nitrous Oxide - 8	https://ClinicalTrials.gov/show/NCT00000256	Completed	University of Chicago	1996-11-30
NCT00000255	Differential Acute Tolerance Development to Effects of Nitrous Oxide - 7	https://ClinicalTrials.gov/show/NCT00000255	Completed	University of Chicago	1996-05-31
NCT00000253	Effects of Nitrous Oxide: A Dose-Response Analysis - 5	https://ClinicalTrials.gov/show/NCT00000253	Completed	University of Chicago	1996-03-31
NCT00000252	Lack of Acute Tolerance Development to Effects of Nitrous Oxide - 4	https://ClinicalTrials.gov/show/NCT00000252	Completed	University of Chicago	1996-06-30
NCT00000251	Effects of Subanesthetic Concentrations of Isoflurane/Nitrous Oxide - 3	https://ClinicalTrials.gov/show/NCT00000251	Completed	University of Chicago	1996-01-31
NCT00000250	Cold Water Immersion Modulates Reinforcing Effects of Nitrous Oxide - 2	https://ClinicalTrials.gov/show/NCT00000250	Completed	University of Chicago	1995-05-31
NCT00000249	Effects of Subanesthetic Concentrations of Nitrous Oxide - 1	https://ClinicalTrials.gov/show/NCT00000249	Completed	University of Chicago	1995-06-30
NCT00000244	Effects of Dynorphin 1-13 on Heroin Addiction - 1	https://ClinicalTrials.gov/show/NCT00000244	Completed	University of Minnesota	1997-03-31
NCT00000240	Combined Buprenorphine and Behavioral Treatment With and Without Contingent Reinforcement on Opioid and Cocaine Abstinence. - 22	https://ClinicalTrials.gov/show/NCT00000240	Completed	University of Vermont	NA
NCT00000239	Buprenorphine Pharmacology Related to Addiction Treatment - 21	https://ClinicalTrials.gov/show/NCT00000239	Completed	National Institute on Drug Abuse (NIDA)	NA
NCT00000238	Temporal Discounting Delayed Outcomes on Opioid-Dependent Outpatients - 20	https://ClinicalTrials.gov/show/NCT00000238	Completed	National Institute on Drug Abuse (NIDA)	NA
NCT00000237	Buprenorphine Detoxification - BBDVI - 19	https://ClinicalTrials.gov/show/NCT00000237	Completed	National Institute on Drug Abuse (NIDA)	NA
NCT00000236	Buprenorphine Pharmacology Related to Addiction Treatment - 18	https://ClinicalTrials.gov/show/NCT00000236	Completed	National Institute on Drug Abuse (NIDA)	NA
NCT00000235	Alternate Day Buprenorphine Administration, Phase XII - 17	https://ClinicalTrials.gov/show/NCT00000235	Completed	National Institute on Drug Abuse (NIDA)	NA
NCT00000234	Alternate Day Buprenorphine Administration, Phase XI - 16	https://ClinicalTrials.gov/show/NCT00000234	Completed	University of Vermont	NA
NCT00000233	Alternate Day Buprenorphine Administration, Phase X - 15	https://ClinicalTrials.gov/show/NCT00000233	Completed	National Institute on Drug Abuse (NIDA)	NA
NCT00000232	Alternate Day Buprenorphine Administration, Phase IX - 14	https://ClinicalTrials.gov/show/NCT00000232	Completed	University of Vermont	NA
NCT00000231	Buprenorphine Detoxification With Two Types of Treatment. BBD IV - 13	https://ClinicalTrials.gov/show/NCT00000231	Completed	National Institute on Drug Abuse (NIDA)	NA
NCT00000230	Buprenorphine Detoxification With Two Types of Treatment. BBD III - 12	https://ClinicalTrials.gov/show/NCT00000230	Completed	University of Vermont	NA
NCT00000229	Buprenorphine Detox With Two Types of Treatment. BBD II - 11	https://ClinicalTrials.gov/show/NCT00000229	Completed	University of Vermont	NA
NCT00000228	Buprenorphine Detox With Two Types of Treatment. BBD I - 10	https://ClinicalTrials.gov/show/NCT00000228	Completed	National Institute on Drug Abuse (NIDA)	NA
NCT00000227	Alternate-Day Buprenorphine Administration. Phase VIII - 9	https://ClinicalTrials.gov/show/NCT00000227	Completed	University of Vermont	NA
NCT00000226	Alternate-Day Buprenorphine Administration. Phase VII - 8	https://ClinicalTrials.gov/show/NCT00000226	Completed	National Institute on Drug Abuse (NIDA)	NA
NCT00000225	Alternate-Day Buprenorphine Administration. Phase VI - 7	https://ClinicalTrials.gov/show/NCT00000225	Completed	National Institute on Drug Abuse (NIDA)	NA
NCT00000224	Alternate-Day Buprenorphine. Phase V - 6	https://ClinicalTrials.gov/show/NCT00000224	Completed	National Institute on Drug Abuse (NIDA)	NA
NCT00000223	Alternate-Day Buprenorphine Administration. Phase IV - 5	https://ClinicalTrials.gov/show/NCT00000223	Completed	National Institute on Drug Abuse (NIDA)	NA
NCT00000222	Alternate-Day Buprenorphine Administration. Phase II - 4	https://ClinicalTrials.gov/show/NCT00000222	Completed	National Institute on Drug Abuse (NIDA)	NA
NCT00000221	Alternate-Day Buprenorphine Administration. Phase I - 3	https://ClinicalTrials.gov/show/NCT00000221	Completed	National Institute on Drug Abuse (NIDA)	NA
NCT00000220	Gradual Vs. Rapid Buprenorphine Detoxification - 2	https://ClinicalTrials.gov/show/NCT00000220	Completed	National Institute on Drug Abuse (NIDA)	NA
NCT00000219	Buprenorphine Dose Alteration Study - 1	https://ClinicalTrials.gov/show/NCT00000219	Completed	University of Vermont	NA
NCT00015171	Buprenorphine and Naloxone for the Treatment of Opiate Dependence - 1	https://ClinicalTrials.gov/show/NCT00015171	Completed	National Institute on Drug Abuse (NIDA)	1997-05-31
NCT00015041	Buprenorphine Dose Escalation Trial for Treatment of Non-Dependent Opiate Users - 2	https://ClinicalTrials.gov/show/NCT00015041	Completed	National Institute on Drug Abuse (NIDA)	1998-06-30
NCT00015028	Buprenorphine/Naloxone for Opiate-Dependence Treatment - 1	https://ClinicalTrials.gov/show/NCT00015028	Completed	National Institute on Drug Abuse (NIDA)	1996-12-31
NCT00000209	Buprenorphine Dosing Interval - 5	https://ClinicalTrials.gov/show/NCT00000209	Completed	National Institute on Drug Abuse (NIDA)	NA
NCT00000208	Methadone/Buprenorphine Cross-Over Study - 4	https://ClinicalTrials.gov/show/NCT00000208	Completed	National Institute on Drug Abuse (NIDA)	NA
NCT00000207	Multicenter Clinical Trial of Buprenorphine - 3	https://ClinicalTrials.gov/show/NCT00000207	Completed	University of California, Los Angeles	1997-04-30
NCT00000206	Clinical Rescue Protocol - 2	https://ClinicalTrials.gov/show/NCT00000206	Completed	University of California, Los Angeles	2005-08-31
NCT00000205	Buprenorphine Maintenance Protocol - 1	https://ClinicalTrials.gov/show/NCT00000205	Completed	University of California, Los Angeles	1993-03-31
NCT00000204	Buprenorphine Maintenance for Opioid Addicts - 3	https://ClinicalTrials.gov/show/NCT00000204	Completed	Yale University	2006-05-31
NCT00000203	Buprenorphine Maintenance for Opioid Addicts - 2	https://ClinicalTrials.gov/show/NCT00000203	Completed	Yale University	2006-05-31
NCT00000202	Buprenorphine Maintenance for Opioid Addicts - 1	https://ClinicalTrials.gov/show/NCT00000202	Completed	Yale University	2006-05-31

Observational Studiess

#If less then 500 studies

nct_id	brief_title	link	overall_status	source	primary_completion_date
NCT03245931	Hepatitis C Education for Pregnant Women With Opiate Addiction - Phase 1	https://ClinicalTrials.gov/show/NCT03245931	Completed	TriHealth Inc.	2019-08-26
NCT03036917	Cognitive Function Before and After Opioid Reduction in Patients With Chronic Pain	https://ClinicalTrials.gov/show/NCT03036917	Completed	Zealand University Hospital	2019-05-03
NCT02941809	Harnessing Placebo Effects in Methadone Treatment	https://ClinicalTrials.gov/show/NCT02941809	Enrolling by invitation	University of Maryland, Baltimore	2020-07-31
NCT02797990	Conflict Between Maternal Autonomy and Child Health in Substance-use	https://ClinicalTrials.gov/show/NCT02797990	Completed	London School of Hygiene and Tropical Medicine	2016-08-31
NCT02751762	A Prospective Investigation of the Risks of Opioid Misuse, Abuse, and Addiction Among Patients Treated With Opioids for the Treatment of Chronic Pain	https://ClinicalTrials.gov/show/NCT02751762	Recruiting	Member Companies of the Opioid PMR Consortium	2020-10-31
NCT02718352	A Naturalistic Study of Adolescents and Young Adults in Treatment for Opioid Dependence	https://ClinicalTrials.gov/show/NCT02718352	Completed	Yale University	2018-02-28
NCT02678507	A Quantitative Study to Assess the Construct Validity of the Prescription Opioid Misuse and Abuse Questionnaire	https://ClinicalTrials.gov/show/NCT02678507	Completed	Member Companies of the Opioid PMR Consortium	2017-06-21
NCT02668549	Cross-Sectional Study to Define and Validate “Doctor/Pharmacy Shopping” as Outcomes Suggestive of Abuse and/or Addiction	https://ClinicalTrials.gov/show/NCT02668549	Completed	Member Companies of the Opioid PMR Consortium	2017-08-09
NCT02667262	An Observational Study to Develop Algorithms for Identifying Opioid Abuse and Addiction Based on Admin Claims Data	https://ClinicalTrials.gov/show/NCT02667262	Completed	Member Companies of the Opioid PMR Consortium	2017-05-17
NCT02667210	Study to Eval Relation Btw Doctor/Pharmacy Shopping & Outcomes of Misuse, Diversion, Abuse, Addiction by Med Rec Review	https://ClinicalTrials.gov/show/NCT02667210	Completed	Member Companies of the Opioid PMR Consortium	2017-06-21
NCT02667197	Study to Validate Coded Medical Terms Used to Identify Opioid-Related Overdose in Databases Used for PMR Study 1B	https://ClinicalTrials.gov/show/NCT02667197	Completed	Member Companies of the Opioid PMR Consortium	2017-05-17
NCT02667158	A Survey to Eval the Relation Between Doctor/Pharmacy Shopping and Outcomes Suggestive of Misuse, Abuse and/or Diversion	https://ClinicalTrials.gov/show/NCT02667158	Completed	Member Companies of the Opioid PMR Consortium	2018-12-19
NCT02660619	Validation of PRISM-5-Op, Measure Of Addiction To Prescription Opioid Medication	https://ClinicalTrials.gov/show/NCT02660619	Completed	Member Companies of the Opioid PMR Consortium	2017-11-28
NCT02657148	Immediate Postpartum Nexplanon Placement in Opioid Dependent Women	https://ClinicalTrials.gov/show/NCT02657148	Completed	University of Pittsburgh	2018-08-31
NCT02583243	Project BEST: Buprenorphine Entry Into Substance Abuse Treatment	https://ClinicalTrials.gov/show/NCT02583243	Completed	Yale University	2008-08-31
NCT02571400	Prevalence and Predictors of Prolonged Post-surgical Opioid Use: a Prospective Observational Cohort Study	https://ClinicalTrials.gov/show/NCT02571400	Completed	University of Notre Dame Australia	2016-10-31
NCT02247024	Pupil Response in Patients on Opioids.	https://ClinicalTrials.gov/show/NCT02247024	Completed	Oslo University Hospital	2018-08-31
NCT02120612	Increasing Patient Knowledge of the Signs of Opioid Overdose and Naloxone in a Suburban Treatment Program	https://ClinicalTrials.gov/show/NCT02120612	Recruiting	Edward-Elmhurst Health System	2020-10-31
NCT02017041	Using mHealth to Aid Opioid Medication Adherence Pilot Study	https://ClinicalTrials.gov/show/NCT02017041	Completed	Care Team Solutions	2014-06-30
NCT01940588	Neuropsychoanalytic Treatment of Failed Back Surgery Syndrome-Opioid Dependence	https://ClinicalTrials.gov/show/NCT01940588	Completed	State University of New York - Upstate Medical University	2013-06-30
NCT01722435	Completion of OST - a Prospective Study	https://ClinicalTrials.gov/show/NCT01722435	Completed	Universitätsklinikum Hamburg-Eppendorf	2014-02-28
NCT01592461	Starting Treatment With Agonist Replacement Therapies Follow-up Study	https://ClinicalTrials.gov/show/NCT01592461	Completed	University of California, Los Angeles	2016-08-31
NCT01570699	Variation of COMT Val158Met Polymorphism Between COM-ON Patients and METHADOSE Patients	https://ClinicalTrials.gov/show/NCT01570699	Completed	Assistance Publique - Hôpitaux de Paris	2016-06-30
NCT01558973	FMRI of Stress and Addictive Disorders	https://ClinicalTrials.gov/show/NCT01558973	Completed	Yale University	2015-12-31
NCT01536925	Studies of Opioid Seeking Behavior: Yohimbine and Hydrocortisone Effects	https://ClinicalTrials.gov/show/NCT01536925	Completed	Wayne State University	2017-04-30
NCT01422837	ALK21-025: Vivitrol’s Cost and Treatment Outcomes Registry	https://ClinicalTrials.gov/show/NCT01422837	Completed	Alkermes, Inc.	2013-10-31
NCT04251208	MOms in REcovery (MORE) Study: Defining Optimal Care	https://ClinicalTrials.gov/show/NCT04251208	Recruiting	Trustees of Dartmouth College	2021-10-31
NCT04059016	Innovatively Increasing PCP Prescribing of Buprenorphine: Measurement Based Care and Integrated Electronic Solution	https://ClinicalTrials.gov/show/NCT04059016	Active, not recruiting	University of Texas Southwestern Medical Center	2021-05-31
NCT03961789	Assessment of the Satisfaction of Patient Undergoing Opioid Replacement Therapy Toward Their Management in Community Pharmacy	https://ClinicalTrials.gov/show/NCT03961789	Recruiting	University Hospital, Clermont-Ferrand	2019-09-30
NCT03947749	Linking Epigenomics With Prescription Opioid Abuse and High Impact Musculoskeletal Pain	https://ClinicalTrials.gov/show/NCT03947749	Recruiting	University of Florida	2022-06-30
NCT03936985	Validation of a Community Pharmacy-Based Prescription Drug Monitoring Program Risk Screening Tool	https://ClinicalTrials.gov/show/NCT03936985	Recruiting	University of Utah	2020-08-30
NCT03932799	Prevent Unsafe Opioid Prescribing	https://ClinicalTrials.gov/show/NCT03932799	Enrolling by invitation	University of Washington	2021-09-30
NCT03925610	Recovery of Ventilation After General Anesthesia in Morbidly Obese Patients	https://ClinicalTrials.gov/show/NCT03925610	Recruiting	Stanford University	2020-09-15
NCT03859778	Evaluation of Pharmacy Students’ Perception of Opioid / Opiate Dependence	https://ClinicalTrials.gov/show/NCT03859778	Completed	University Hospital, Clermont-Ferrand	2019-03-31
NCT03845699	Development of an Algorithm That Predicts Hypoventilation Due to an Opioid Overdose	https://ClinicalTrials.gov/show/NCT03845699	Recruiting	RTM Vital Signs, LLC	2020-05-14
NCT03743493	PCORnet Opioid Surveillance Study	https://ClinicalTrials.gov/show/NCT03743493	Active, not recruiting	Louisiana Public Health Institute	2019-04-15
NCT03685162	Observational Study to Evaluate Levomethadone Safety and Effectiveness in Subjects Under Opioid Maintenance Treatment	https://ClinicalTrials.gov/show/NCT03685162	Recruiting	L.Molteni & C. dei F.lli Alitti-Soc. di Esercizio S.p.A.	2023-02-28
NCT03635346	Medicinal Dependence and Chronic Pain: Addictive Evaluation in CETD	https://ClinicalTrials.gov/show/NCT03635346	Completed	University Hospital, Brest	2016-09-03
NCT03604861	An Observational Study of Environmental and SocioEconomic Factors in Opioid Recovery	https://ClinicalTrials.gov/show/NCT03604861	Completed	Indivior Inc.	2019-03-31
NCT03603158	KCNH2 Polymorphisms on the QTc Interval in Kelantanese Malays Patients Receiving Methadone Maintenance Therapy (MMT)	https://ClinicalTrials.gov/show/NCT03603158	Completed	Universiti Sains Malaysia	2012-12-31
NCT03583138	HIV, Buprenorphine, and the Criminal Justice System (STRIDE2)	https://ClinicalTrials.gov/show/NCT03583138	Completed	Yale University	2015-12-15
NCT03495388	PG and PK of Oxycodone to Personalize Post-op Pain Management Following Surgery in Children	https://ClinicalTrials.gov/show/NCT03495388	Recruiting	Indiana University	2020-03-31
NCT03427424	Imaging Biomarker for Addiction Treatment Outcome	https://ClinicalTrials.gov/show/NCT03427424	Recruiting	National Institutes of Health Clinical Center (CC)	2022-12-31
NCT03422211	A Prospective Assessment of Opioid Utilization Post-operatively in Sports Orthopaedic Surgeries	https://ClinicalTrials.gov/show/NCT03422211	Active, not recruiting	St. Louis University	2018-11-06
NCT01191242	Methadone Monitoring for Insights Into Adverse Events	https://ClinicalTrials.gov/show/NCT01191242	Completed	Intermountain Health Care, Inc.	2011-03-31
NCT01108679	Neurocognitive Effects of Buprenorphine Among HIV+ and HIV-Opioid Users	https://ClinicalTrials.gov/show/NCT01108679	Completed	Albert Einstein College of Medicine	2012-02-01
NCT00857350	The Prevalence of HIV Drug Resistance and Transmission Risk in Opioid Agonist Treatment	https://ClinicalTrials.gov/show/NCT00857350	Completed	Yale University	2010-06-30
NCT02660606	A Qualitative Study to Assess the Content Validity of the Prescription Opioid Misuse and Abuse Questionnaire	https://ClinicalTrials.gov/show/NCT02660606	Completed	Member Companies of the Opioid PMR Consortium	2016-01-18
NCT02863601	Impact of Pregnancy on Buprenorphine Pharmacokinetics and Pharmacodynamics	https://ClinicalTrials.gov/show/NCT02863601	Recruiting	University of Pittsburgh	2021-06-30
NCT00687089	Examination of Cognitive Function in Patients Treated With Subutex	https://ClinicalTrials.gov/show/NCT00687089	Completed	BeerYaakov Mental Health Center	2009-01-31
NCT00725608	Acceptability and Safety of Switching From Subutex or Other Opioid Drug Dependence Therapy to Suboxone (NIS P05444)	https://ClinicalTrials.gov/show/NCT00725608	Completed	Indivior Inc.	2011-04-30
NCT00723749	Treatment of Opioid Dependent Patients With Suboxone: Acceptability & Safety Data From Real Life Scenario (Study P05603)	https://ClinicalTrials.gov/show/NCT00723749	Completed	Indivior Inc.	2010-12-31
NCT00723697	Observational Study of Misuse of High Dose Buprenorphine (Subutex® or Generic) in Opiate-Addicted Patients in France (Study P05186AM1)(COMPLETED)	https://ClinicalTrials.gov/show/NCT00723697	Completed	Indivior Inc.	2010-02-28
NCT00698737	Treatment Study: Reducing Cocaine/Heroin Abuse With SR-Amphetamine and Buprenorphine (ARC)	https://ClinicalTrials.gov/show/NCT00698737	Completed	Wayne State University	2012-11-30
NCT00684840	Effects of Stress and Other Factors on Opiate Drug Choice.	https://ClinicalTrials.gov/show/NCT00684840	Completed	Wayne State University	2011-12-31
NCT00608504	Effects of Environmental Factors on Opiate Drug Choice in Opioid Dependent Individuals.	https://ClinicalTrials.gov/show/NCT00608504	Completed	Wayne State University	2009-04-30
NCT00473993	Hepatitis C Among Opioid Addicts in Opioid Maintenance Treatment in Zurich, Switzerland	https://ClinicalTrials.gov/show/NCT00473993	Completed	Seidenberg, Arztpraxis A., M.D.	NA
NCT00471042	Study of Buprenorphine Maintenance Treatment for Opioid Dependence in Primary Care	https://ClinicalTrials.gov/show/NCT00471042	Completed	New York State Psychiatric Institute	2008-08-31
NCT00439049	Substance Abuse Pre-Treatment Screening Study	https://ClinicalTrials.gov/show/NCT00439049	Recruiting	The University of Texas Health Science Center, Houston	2021-06-30
NCT00429767	Sustained Release d-Amphetamine & Buprenorphine on Drug Seeking Behavior in Opioid & Cocaine Dependent Individuals	https://ClinicalTrials.gov/show/NCT00429767	Completed	Wayne State University	2010-01-31
NCT00292136	Real Time Assessment of Drug Craving, Use, and Abstinence During Outpatient: A Development and Feasibility Study	https://ClinicalTrials.gov/show/NCT00292136	Completed	National Institutes of Health Clinical Center (CC)	NA
NCT00237406	Interactive Voice Response (IVR) for Methadone Patients	https://ClinicalTrials.gov/show/NCT00237406	Completed	Butler Hospital	NA
NCT00227357	The CORE Buprenorphine Project - An HIV Primary Care Program Demonstration	https://ClinicalTrials.gov/show/NCT00227357	Completed	Ruth M. Rothstein CORE Center	2008-12-31
NCT00218621	The Effects of Methadone and Buprenorphine on Fetal Neurobehavior and Infant Neonatal Abstinence Syndrome - 1	https://ClinicalTrials.gov/show/NCT00218621	Completed	Johns Hopkins University	2009-02-28
NCT00218361	Effects of Post-Session Supplemental Hydromorphone on Drug Seeking Behavior in Opioid Dependent Individuals	https://ClinicalTrials.gov/show/NCT00218361	Completed	Wayne State University	NA
NCT00218309	Effects of Pre-Session Supplemental Hydromorphone on Drug Seeking Behavior in Opioid Dependent Individuals	https://ClinicalTrials.gov/show/NCT00218309	Completed	National Institute on Drug Abuse (NIDA)	NA
NCT00218010	Methadone Levels in Breast Milk of Women Taking Methadone for Opiate Addiction - 2	https://ClinicalTrials.gov/show/NCT00218010	Completed	National Institute on Drug Abuse (NIDA)	2005-08-31
NCT00170339	Bone Density and Serum Testosterone in Male Methadone Maintained Patients	https://ClinicalTrials.gov/show/NCT00170339	Completed	Hennepin Healthcare Research Institute	NA
NCT00067184	Fetal Neurobehavioral Development in Methadone Maintained Pregnancies	https://ClinicalTrials.gov/show/NCT00067184	Completed	Johns Hopkins University	2010-08-31
NCT00000265	Subjective Effects of Nitrous Oxide in Dental Patients - 17	https://ClinicalTrials.gov/show/NCT00000265	Completed	University of Chicago	2002-01-31

Registries

#If less then 500 registries

nct_id	brief_title	link	overall_status	source	primary_completion_date
NCT03161795	Addressing the Risks of Long-Term Opioid Therapy in Chronic Noncancer Pain	https://ClinicalTrials.gov/show/NCT03161795	Completed	Seoul National University	2018-01-19
NCT02969668	Interferon-free Antiviral Treatment of Chronic Hepatitis C Virus Infection Among Opioid-substituted Patients	https://ClinicalTrials.gov/show/NCT02969668	Active, not recruiting	Universitätsklinikum Hamburg-Eppendorf	2018-10-31
NCT03729388	Treatment for Opiate Addiction: Prognostic fActors of Responsiveness to Maintenance Treatment	https://ClinicalTrials.gov/show/NCT03729388	Recruiting	Nantes University Hospital	2021-03-01
NCT03611335	A Pragmatic Trial of the Consult for Addiction Treatment and Care in Hospitals (CATCH) Model for Engaging Patients in Opioid Use Disorder Treatment	https://ClinicalTrials.gov/show/NCT03611335	Enrolling by invitation	NYU Langone Health	2022-08-31
NCT03570099	Naloxone Treatment in Skåne County - Effect on Drug-related Mortality and Overdose-related Complications	https://ClinicalTrials.gov/show/NCT03570099	Recruiting	Region Skane	2020-07-01